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KMID : 0391519940020010129
Journal of the Korean Child Neurology Society
1994 Volume.2 No. 1 p.129 ~ p.143
A Clinical Study on Characteristics and Relapsing Factors of Juvenile Myasthenia Gravis in Korea



Abstract
Juvenile myasthenia gravis(JMG) is quite well known to be caused by the autoimmune mechanism In addition. there are some opinions that MG is different from Caucasians and Oriental races.
@ES The results were summarized as follows:
@EN The male to female ratio was 1:1.4 In 39(71%) cases of patients, the age at onset was between and 6 years(mean 4.9 years) and 20(38%) cases were seen in spring time, All patients were initially treated with anticholinesterase but 46(84%)
cases
also
required immunosuppressive therapies. Complete remission occurred in 4patients(6%), Phamarcologic remission in 22 (40%), Marked improvement in 11(20%), Mild improvement in 9(17%), No change or Worsening in 9(17%). The mean interval between intial
therapy and symptomatic improvement was 12.1 days. 26 cases were relapsd and the mean interval between the pharmacologic remission and onset of symptoms was 10.3 months. The major factors to relapse were reducing dosages and infections. All of
these
findings indicate that Juvenile myasthenia gravis has some differences between Caucasians and Koreans and attentions are needed for the proper management.
KEYWORD
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